A generic signaling cascade is shown in the following figure, A... | Filo
A generic signaling cascade is shown in the following figure, A... …
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2. Consider the following hypothetical signaling cascade diagramed below. A growth factor binds to a receptor, which triggers a protein kinase cascade. In the first step, the intracellular domain of the receptor phosphorylates and activates a protein kinase. When active, the protein kinase phosphorylates a transcription factor in the cytoplasm. Phosphorylation of the transcription factor promotes binding of a nuclear shuttling factor that trans-locates the transcription factor into the nucleus w
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