BMJ Open

Study protocol for optimising antipsychotic prescribing among hospitalised patients in the acute care setting in Scotland: a national retrospective cohort study

Introduction Prescribing high-dose antipsychotics is typically reserved for individuals with treatment-resistant severe ...
eLife

Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface

An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα ...
eLife

Continuous flashing suppression of V1 responses and the perceptual consequences revealed via two-photon calcium imaging and transformer modeling

Two-photon imaging and ocular dominance mapping. A. Optical windows for imaging of two macaques. Green crosses indicate the regions for viral vector injections, and yell ...
Thorax

Critical care research in low- and middle-income countries: a narrative review

Critical illness poses a significant global health challenge, disproportionately affecting low- and middle-income countries (LMICs) and other low-resource settings, where healthcare resources and ...