The methylation state of the paternal genome is rapidly reprogrammed shortly after fertilization. Recent studies have revealed that loss of 5-methylcytosine (5mC) in zygotes correlates with appearance ...

Researchers in Michigan published a study “Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes” in Nature Communications that shows ...

Mammalian genomes have been colonised by transposable elements (TEs), so called ‘genetic parasites’, which occupy ~ 50% of genomic DNA and harbour the potential to propagate, resulting in genetic ...

A new study from the MRC Laboratory of Medical Sciences (LMS) in London, UK reveals how ancient viral DNA once written off as ...

Transposable elements are stretches of DNA that can move around the genome. Many of these DNA sequences originate from long ...

The viral transposable element, MERVL, acts as a central switch during early embryonic development, driving totipotent gene ...

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection. The findings in ...

A new study shows that transposable elements play an important role in regulating genetic expression with implications to advance the understanding of genetic evolution. Until recently, little was ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...

Transposable elements, remnants of ancient viral DNA, are reactivated during the first hours and days following fertilization. This dynamic period of early development sees embryonic cells displaying ...