Mice bearing the PDGF-Rα-GFP construct were described (13). Production of green-fluorescent protein (GFP) is controlled by the endogenous pdgf-rα promoter. GFP expression in PDGF-Rα-GFP mice spatially ...

Platelet-derived growth factors (PDGFs) are mitogenic during early development, promoting the proliferation of undifferentiated mesenchymal cells and specific progenitor populations. At later ...

Expert Rev Ophthalmol. 2013;8(6):527-537. In patients that underwent cataract surgery, baseline aqueous levels of IL-6, IP-10, VEGF and macrophage chemotactic protein (MCP)-1 were higher in patients ...

Expert Rev Ophthalmol. 2013;8(5):475-484. Together, these preclinical data indicate that both antibody and small kinase-based VEGF/PDGF antagonists are effective in animal models of pathologic ocular ...

“The present study analyzed PDGFR and VEGFR expression in primary colon cancer tissues and CRC cell lines in order to better define their expression profiles. Furthermore, we analyzed putative PDGF ...

Scientists from Tokyo Metropolitan University have discovered that a protein called platelet-derived growth factor subunit B (PDGF-B) is continuously secreted from skeletal muscle cells and helps to ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have discovered that a protein called platelet-derived growth factor subunit B (PDGF-B) is continuously secreted from skeletal muscle cells ...

Potentiating the effect of chemotherapy with low-dose fractionated radiation (LDFRT) in locally advanced squamous cell carcinoma of the head and neck (SCCHN) ...

Las Vegas(KLAS)-PDGF stands for Platelet-Derived Growth Factor — a breakthrough regenerative treatment that uses highly concentrated growth factors from your own plasma to repair and rejuvenate the ...

The receptors for vascular endothelial growth factor and platelet-derived growth factor (VEGFR-2 and PDGFR) play essential and complementary roles in angiogenesis, and combined inhibition of these ...

PRINCETON, N.J., April 26 /PRNewswire/ -- Ophthotech Corp. ("Ophthotech"), a privately held biopharmaceutical company focused on developing ophthalmic therapies for back-of-the-eye diseases, today ...