Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Three water-soluble egg yolk fractions (FA, FB, and FC) and subfractions of FC (FC1 (< 3 kDa) and FC2 (> 3 kDa)) showed promising osteoclastogenesis inhibitory effects by suppressing osteoclast ...

When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease.

Furthermore, the number of osteocyte dendrites-elongated structures that help in regulation of bone remodeling-was reduced in the mutant mice. Additional genomic analysis of cells obtained from the ...