Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

Female ginseng has long been used in traditional Chinese medicine for osteoporosis treatment. A new compound that affects osteoclast formation has been derived from the plant Angelica sinensis, ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

During osteoclast differentiation, Ctdnep1 expression remains consistent, yet its depletion results in heightened osteoclast formation and activity. Mechanistically, Ctdnep1 demonstrates a suppressive ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts. This ...