A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem of ...

Scientists from Cornell University, University of California, San Francisco (UCSF), and elsewhere have found that a surplus of membrane proteins may help bacteria survive antibiotic exposure. These ...

In a recent study published in the journal Nature, researchers in the United States of America designed and discovered lolamicin, a selective antibiotic that targets the lipoprotein transport system ...

Researchers have determined a protein’s essential role in bacterial envelope structure and function, which could inspire a search for better antibiotics. Researchers at Johns Hopkins University (MD, ...

Vancomycin is a common antibiotic used to treat gram-positive bacterial infections. It targets a key building block of the bacterial cell wall called Lipid II, but it can’t reach this lipid in ...

To date combination therapy for infections by CR GNB is not supported by evidence from a series of adequately sized RCTs. However, pre-clinical data and emerging clinical evidence from observational ...