a, NMR-derived structure of a G-quadruplex, showing the flanking bases and potential drug binding sites 9. b, Visualization of G-quadruplex structures in chromosomes in HeLa cells using ...

DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...

A collaboration led by Distinguished Professor Dr. Kazunori Ikebukuro from Tokyo University of Agriculture and Technology (TUAT), Japan, discovered that G-quadruplex (G4)-forming DNA binds myoglobin ...

Not all DNA is in the double helix form described in textbooks since the 1950’s. Quadruple helix DNA, also known as G-quadruplex DNA, was identified in the human genome several decades ago, and ...