Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified ...

Minor groove binding compounds represent a diverse class of small molecules that interact with the DNA double helix by inserting into its narrower, minor groove. This mode of binding affords a unique ...

For the first time, a synthetic compound has been made that can bind to DNA in the cells' energy powerhouses, suppressing a gene associated with nerve and muscle disease. Pyrrole-imidazole polyamides ...

Compared to newborns conceived traditionally, newborns conceived through in vitro fertilization (IVF) are more likely to have certain chemical modifications to their DNA, according to a study by ...

According to subsection 4 of new §1(a) of the German Patent Act (GPA) implementing EU Directive 98/44/EC, a claim to a naturally occurring DNA sequence must recite the use of the DNA. There appears to ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...