Characterizing clonal evolution in blood cancers like acute myeloid leukemia (AML) is critical for understanding their mutational histories and how cell populations change during disease development.

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

A genome study has proven that all specimen of Marmorkrebs, or marbled crayfish, originate from a single female. About 30 years ago, the original clone evolved in an aquarium. Ever since, the female ...

A recent review by Carlo Maley, a researcher at Arizona State University, and Lucie Laplane from the University of Paris Pantheon-Sorbonne critiques the dominant theory of cancer evolution. The ...